Which of the following is considered a relative contraindication to fibrinolytics?

The consideration of relative contraindication to fibrinolytics is crucial in patient management, particularly in emergency settings where the risks and benefits must be weighed carefully. Active peptic ulcer disease is classified as a relative contraindication because, while it does pose a risk of significant bleeding if fibrinolytics are administered, it does not render treatment completely off-limits.

Fibrinolytics, which are used to dissolve blood clots in conditions such as myocardial infarction or pulmonary embolism, can cause bleeding. In patients with a history of active peptic ulcer disease, the risk of exacerbating the condition and causing gastrointestinal bleeding is a concern, but it may still be justifiable to administer the treatment if the benefits—such as preventing significant morbidity or mortality from a clot—outweigh the risks.

Conversely, the other scenarios—active bleeding, recent surgery, and uncontrolled hypertension—are typically regarded as absolute contraindications. In cases of active bleeding, the risk is overtly increased as the condition could lead to life-threatening hemorrhage. Recent surgery carries the same risk, particularly if the surgery involved a major organ or area where bleeding can be difficult to control. Uncontrolled hypertension poses a high risk for hemorrhagic stroke when fibrinolytics are