What is the necessary MAP range for maintaining cerebral auto regulation?

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The necessary mean arterial pressure (MAP) range for maintaining cerebral auto-regulation is 50-150 mm Hg. This range is critical for ensuring that the brain receives a consistent blood supply despite fluctuations in systemic blood pressure. Cerebral auto-regulation allows the blood vessels in the brain to constrict or dilate to maintain stable cerebral blood flow, protecting neural tissues from ischemia or hyperemia, both of which can lead to significant neurological damage.

When MAP falls below 50 mm Hg, the ability of the cerebrovascular system to auto-regulate can be compromised, leading to insufficient blood flow, which can cause ischemia. Conversely, when MAP exceeds 150 mm Hg, there's a risk of vascular injury and increased intracranial pressure due to excessive blood flow. Therefore, the 50-150 mm Hg range is crucial for optimal cerebral perfusion and overall brain health. Understanding this range is vital for healthcare professionals working in critical care settings to ensure appropriate blood pressure management in patients.

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